What are NIH’s 7 principles of ethics in research?
The National Institutes of Health (NIH) has defined seven principles to protect clinical research participants and promote research ethics:
Social and clinical value: the scientific advances of a research study should justify the costs or risks of conducting this research.
Scientific validity: a study should be designed to address an answerable question using feasible and accepted research methods.
Fair subject selection: participants should be selected based on the scientific aims of the study and should not be included or excluded for reasons unrelated to research goals.
Favorable risk-benefit ratio: the potential risks to participants should be minimized and should be outweighed by potential benefits.
Independent review: an independent review panel should ensure a study is ethical before research begins.
Informed consent: participants should decide whether to voluntarily participate in a study after learning about its research question, methods, potential risks, and benefits.
Respect for potential and enrolled subjects: individuals should be treated with respect throughout the research process.